THE IODINE DEFICIENCY EPIDEMIC:
LINKED TO THYROID & BREAST DISEASES, CANCER, & OBESITY.
LINKED TO MENTAL RETARDATION IN CHILDREN.

Summary by Laura Power, PhD, LDN
Based on work of: Guy Abraham, MD, David Brownstein, MD, and Linnette Beck

There is an epidemic of Iodine deficiency in this country – one that affects every man, woman and child – and especially vegetarians. Over the last 30 years our Iodine intake has declined 50% (removed from our food supply!), while the ingestion of toxic competing halogens (bromine, fluorine, chlorine, perchlorate) has dramatically increased in food, water, medicines and the environment. [For example: Iodine in wheat has been replaced with Bromine, the gas used to fumigate your house for termites!] Simultaneously there has been a related increase in the rates of thyroid disease, breast cancer, fibrocystic breast disease, prostate cancer, and obesity -- plus developmental delays and mental retardation in children! Meanwhile in Japan Iodine intake is up to 100 times higher, while all of these same diseases are significantly lower!

Symptoms of Iodine or Thyroid Deficiency
Do you have any of these symptoms? Brittle nails, cold hands and feet, cold intolerance, depression, difficulty swallowing, dry skin, dry hair or hair loss, fatigue, high cholesterol, hoarseness, infertility, lethargy, menstrual irregularities, early menopause, poor memory or concentration, slower heartbeat, throat pain, or weight gain. Or more serious diseases: thyroid dysfunction, fibrocystic breast disease, breast cancer, ovarian cancer, endometrial cancer, or prostate cancer? Does your child have any of these symptoms? Developmental delays (ADD, PDD, LD), mental retardation, or Down’s Syndrome. If so, iodine deficiency or hypothyroid could be the cause.

THE 4 FUNCTIONS OF IODINE

1. Thyroid, Metabolism & Weight
Iodine is the key to a healthy thyroid and metabolism. It is best known for being a part of thyroid hormones, which are used in every cell of our bodies to regulate metabolism and weight by controlling the burning of fat for energy and heat. Over 100 years ago iodine was shown to prevent and reverse goiter (swelling of the thyroid) and hypothyroid. Iodine deficiency may also be involved in autoimmune disorders such as Grave’s and Hashimoto’s diseases; as studies have shown iodine-deficient patients have a higher rate of anti-thyroid antibodies.

Iodine also controls metabolism in other ways. It is important for the other endocrine glands: the adrenals, pituitary, gonads (sex glands), pancreas, pineal and thymus. Iodine is also involved in digestion, and is concentrated in the salivary glands and gastric mucosa. It has also been associated with: excess mucus production, fatigue, hemorrhoids, headaches, keloid scarring, and migraine headaches.

There is an epidemic of obesity and overweight in this country. And no wonder! Iodine is crucial for metabolism and weight loss. Iodine stores in fat cells. Toxic halogens can also store in fat cells, blocking the release of fat and blocking weight loss. Low thyroid has long been associated with modest weight gain. But patients with low iodine levels AND accumulation of toxic halogens are showing a disturbing trend of being unable to lose weight beyond a certain plateau. By some estimates 50% to 60% of our population is now considered obese. The best therapy in most cases is high-dose iodine (25 mg/day) combined with L-Tyrosine (1000 mg/day) to make more thyroid hormones. Also essential are dry-heat or far infra-red saunas for detoxification of other halogens, 25% calorie reduction, and consistent exercise.

Symptoms of Thyroid Deficiency

Brittle nails
Cold hands and feet
Cold intolerance
Constipation
Depression
Difficulty swallowing
Dry skin
Elevated cholesterol
Essential hypertension
Eyelid swelling
Fatigue
Hair loss
Hoarseness
 

Hypotension
Inability to concentrate
Infertility
Irritability
Menstrual irregularities
Muscle cramps
Muscle weakness
Nervousness
Poor memory
Puffy eyes
Slower heartbeat
Throat pain
Weight gain

2. Mental Development Vs Retardation
The World Health Organization (WHO) has related iodine deficiency to mental retardation, cretinism, increased child and infant mortality, infertility, and socioeconomic decline -- and more recently developmental delays (ADD, PDD, LD). Iodine and thyroid hormones stimulate the development of the brain and nerves. Hence it is important for intelligence and memory. It was shown to make a difference of 13.5 points on IQ tests between iodine deficient and iodine sufficient areas. Iodine is crucial to brain development, and is concentrated in the brain, cerebrospinal fluid, and the eye, as well as the substantia nigra of the brain (an area associated with Parkinson’s Disease). High amounts of iodine are excreted in breast milk to help develop a baby’s growing brain and nervous system. Some evolutionary biologists believe iodine and eating seafood played an important role in human brain development and evolution.

3. Fertility
The World Health Organization has also related iodine deficiency to infertility. Iodine is most important for women, because it is most highly concentrated in the thyroid, breasts and ovaries. Iodine deficiency can lead to menstrual irregularities, infertility, early menopause, and ovarian diseases. But it is still vital for men, especially for the prostate.

4. Enhanced Immune Function
Iodine is now known to play an essential role in immune function. It has potent anti-bacterial, anti-parasitic, anti-viral, and anti-cancer activity. For centuries it has been used topically to kill bacteria. Until recently it was the leading anti-parasitic drug (yodoxin or iododoxin). High-dose iodine has been shown to kill breast and thyroid cancer cells (induce selective apoptosis). It is also a potent antioxidant. More recently, iodine deficiency has been related to: thyroid cancer, fibrocystic breast disease, breast cancer, ovarian cancer, endometrial cancer, and prostate cancer. In the 1960’s when iodine intake was higher (and toxic halogens lower) the risk for breast cancer was 1 in 20; today it is 1 in 8 and increasing by 1% per year! Iodine deficiency has also been associated with the following: parotid duct stones, sebaceous cysts, and vaginal infections.

CAUSES OF IODINE DEFICIENCIES

Why Are Iodine Levels So Low?
According to the NHANES data iodine levels in the USA have fallen by about 50% over the last 30 years. Why? There are many reasons. According to the World Health Organization, about one-third of the world’s population live in Iodine deficient areas, which affects 129 countries. This is because most of the iodine resides in the sea and seashores, while most inland areas are iodine deficient. Other contributing factors include: diets low in fish, shellfish or seaweed, vegan or vegetarian diets, poor availability of iodine in salt, poor farming techniques, avoidance of salt due to fear of high blood pressure, the ingestion of toxic halogens, and the use of radioactive iodine in many medical procedures (which competes with natural iodine). In addition, past sources of iodine in food have been removed. For example: Iodide was used as a dough conditioner in baked goods from the 1960’s to the 1980’s, but has since been replaced with bromide (a toxic halogen). Cow’s udders and milking buckets were swabbed with iodide to kill germs. But no longer.

The reason is “THE WOLFF-CHAIKOFF EFFECT”, which has been a disaster for iodine. This experiment led to a fear of iodine, and iodine being removed from the American food supply for over 30 years! This paper has been quoted by many, but understood by few. It was misinterpreted, and used to describe a case of hypothyroidism caused by excessive iodine intake. In fact: toxic radioactive iodine was injected intravenously. It had nothing to do with food or supplement iodine intake. And it cannot explain why high intake of natural iodine does not cause the same effect.

New Iodine Lab Tests
Doctors Data Laboratories now offers new Iodine loading tests. These are professional urine test kits, which can be done at home, then shipped to the lab. They are to help determine if you have an iodine deficiency. Cost is $20 for the kit, and $50 prepaid to the lab. Contact your holistic physician or nutritionist for more details.

IODINE THERAPIES

How Much Iodine Do We Need?
The French were the first to use iodine to treat goiter in the early 1800’s. There are two forms: iodine and iodide, each used by certain tissues in the body. The thyroid mainly uses iodide. Dr. Lugol employed 5% iodine and 10% potassium iodide in water to increase solubility. Just two drops of Lugol’s solution supplied 12.5 mg of iodine/iodide daily. This was widely available at apothecaries, and was used to treat goiter, infections, and many other symptoms.

The Japanese have had a high iodine intake for millennia, primarily due to seaweed and seafood. They also add iodine to their eggs through the chicken feed. Their average daily iodine intake is 13.8 mg (about 100 times the U.S. RDA). They have remarkably lower rates of breast, endometrial and ovarian cancer, and significantly lower rates of fibrocystic breast disease and prostate cancer. They also have low rates of obesity, and are noted for their academic achievements.

In the USA from the early 1800’s to the mid 1900’s we had a much higher iodine intake than we do today, especially near the coasts. The National Institutes of Health reported that the average iodine intake in the 1960’s from bakery products alone was 726 mcg/day. Today it is zero. This did not even include seafood.

Today the RDA for iodine in the USA is only 150 mcg/day, 220 mcg during pregnancy, and 290 mcg during lactation. This is the bare minimum needed to prevent goiter, extreme stupidity, and hypothyroidism; but it is not enough to supply the body’s total needs – nor to prevent cancers. A recent article in the New England Journal of Medicine (June 29, 2006) claims that iodine deficiency is still widespread, and argues for an increase to at least 300-400 mcg/day. Too conservative, but moving in the right direction!

So how much iodine do we really need? A lot more than the U.S. RDA. The amount can be calculated based on Dr. Abraham’s extensive research. This shows that with an iodine-loading test of 50 mg in 24 hours, healthy iodine-sufficient subjects excrete 90% and retain 10%. 10% of 50 mg = 5 mg; this is how much we need each day for saturation of iodine receptors and optimal physiological function.

Foods Rich In Iodine
The foods richest in iodine are: seaweed, seafood (shrimp, cod, sea bass, haddock, and perch) and iodized salt. In the USA and other countries iodine has been added to salt since the 1920’s to prevent goiter; but research shows that iodine in salt is only about 10% bioavailable. Iodized salt prevents most goiter, but is not sufficient to supply the rest of the body’s needs. A better approach is to add iodine to bread, as was done in the past, because studies show it is 10 times more bioavailable than salt. A single slice of bread once supplied 150 mcg – one day’s RDA.

New Potent Iodine Supplement
Iodoral is now available through licensed health care providers. It is a high-potency tablet of 5 mg Iodine + 7.5 mg Potassium Iodide (12.5 mg total). This is about the current average adult daily intake of Iodine from food in Japan, and the same as the French Lugol’s Solution that has been safely used for nearly 200 years. It is higher than currently available low-dose supplements (225 mcg). It is for use in correcting long-term iodine deficiency symptoms, and is considered safe and effective. For increasing thyroid, it is best used with L-Tyrosine. See your nutritionist or holistic physician for testing and these special supplements.

Can Excess Iodine Be Harmful?
True allergies are extremely rare. But iodine tolerance varies with individuals. Most reactions to high iodine intake are likely due to the forced excretion of toxic halides, such as bromide, fluoride and perchlorate. Symptoms can include: acne, eczema, rashes, headache, nausea, vomiting, diarrhea, increased salivation, metallic taste in mouth, sneezing, nervousness, palpitations and racing pulse. Caution should be used in cases of Grave’s Disease (hyperthyroid). Dose should be adjusted to tolerance in conjunction with your health care provider.

Symptoms of Excess Iodine

Excess Iodine Symptoms 

Excess Thyroid Hormone

Acne, rashes
Diarrhea
Headache
Increased salivation
Metallic taste in mouth
Nausea
Sneezing

 

Nervousness
Palpitations
Racing pulse


Harmful sources of iodine: Radioactive iodine is used in medical testing and therapy procedures, and can cause allergic reactions, hypothyroid, or certain rare cancers, especially if natural iodine stores are low. Radioactive iodine has also been released in nuclear power plant accidents, and is known to cause thyroid cancers. Other organic iodine compounds are used in certain drugs and radiographic contrast media; their long-term effects are unknown.

THE TOXIC HALOGENS

Halogens are a class of related elements that include iodine, bromine, fluorine and chlorine. When they are chemically “reduced” they become “halides”: iodide, bromide, fluoride, and chloride. These are the forms we usually encounter in foods, medications and the environment. While iodine and chloride are beneficial in small amounts, the others are toxic. They can bind to iodine receptors, block the action of iodine and thyroid hormones, and cause many severe diseases.

Toxic halogens excrete very slowly from the body, because there is no known liver detoxification pathway for them. But excretion can be increased with the following: high-dose iodine, high-dose vitamin C (which aids detoxification), unrefined sea salt (which substitutes chloride for bromide), Epsom salts baths, and sweating in a dry infrared sauna.

Bromine

Bromine is a poison, and has no place in human consumption. Bromine is close in size to iodine, and can bind to iodine receptors blocking their function. Bromide has been substituted for iodide in many foods, medications and the environment – despite the fact that it is a pesticide. It has replaced iodide in all bakery products, reducing our iodine intake by 726 mcg/day.

The ingestion of bromine in an iodine-deficient state will further exacerbate thyroid illness. Bromine intoxication symptoms include: feeling dull, apathetic, depressed, irritable, and headachy, plus hypothyroidism. Severe reactions include: delirium, psychomotor retardation, schizophrenia, and hallucination. Bromine also binds to and damages the iodine transporter (sodium-iodide symporter -- SIS).

Sources of Bromine

Medications 

Foods, Other

Atrovent Inhaler
Atrovent Nasal Spray
Ipratropium Nasal Spray
Spiriva Handihaler
Pro-Panthine
Pyridostigmine bromide
Anesthesia
 

All bakery products
Mountain Dew
AMP Energy Drink
Gatorade – Citrus
Pools & Hot tubs
Fumigant for termites, etc.


Fluoride

Fluoride is a known toxin, and can be lethal. Fluoride has been added to the USA drinking water for over 50 years. This is despite the fact that a New Zealand study found no difference in tooth decay between fluoridated and non-fluoridated water areas. Many European countries have stopped fluoridating. Fluoridation has been linked to dental fluorosis (tooth discoloration), hip fractures, bone cancer, lowered intelligence, and kidney toxicity, plus a cause of goiter in dogs. Fluoride is more toxic when there is an iodine deficiency.

Sources of Fluoride

Medications 

Other

5-Fluorouracil (for skin cancer)
Anesthesia
Flonase
Flovent
Paxil
Prozac
SSRI anti-depressants 

Removed from market:

Astemizole
Baycol
Fen-Phen
Omniflox
Posicor
Propulsid
 

Fluoride dental tablets
Propellants in spray cans
Public Drinking water
The Ozone Layer
Tooth paste


Chlorine

Chloride is an important element in the extracellular fluid and in stomach acid. But in large amounts it is toxic, and (with its byproducts) has been linked to: birth defects, cancer, reproductive disorders, stillbirth, and immune system breakdown. Excess sodium-chloride (table salt) competes with iodine, and was shown to cause hypothyroidism in China.

Sources of Chlorine

Foods: 

Other

Salt
Public Drinking water
Sucralose or Splenda®
(chlorinated table sugar)

Dish washer steam
Hot tubs
Propellants in spray cans
Swimming pools
The Ozone Layer

 


Perchlorate

Perchlorate is one atom of chlorine surrounded by 4 atoms of oxygen. It is a toxin. It can displace iodine in the body and damage iodine transporters. It can cause: hypothyroidism, thyroid cancer, goiter, breast disease, disruption of the menstrual cycle, immune system dysfunction, poor fetal development, and mental retardation of newborns.

Perchlorate is found naturally in the environment and can be manmade. It has become a major contaminant of ground water in 43 states. The entire lower Colorado River is contaminated with perchlorate, affecting 20 million people.

Sources of Perchlorate

Foods: 

Other

*Public Drinking water
Cow milk
Human milk
Lettuce (fall & winter in the SW USA)

 

Car air bags
Leather tanning
Fireworks
Rocket Fuel

 


THE DEDOXBOX SAUNA:
DETOXIFY HALOGENS & OTHER CHEMICALS


In America beneficial iodine has been replaced in our food supply, water supply, medications, and environment by toxic "Halogens" over the last 30 - 50 years. Toxic halogens are chemically related to Iodine, and include: Bromine, Fluorine, Chlorine and Perchlorate. They block iodine receptors in our bodies, and lead to cancers, thyroid disease, and obesity, plus learning disabilities and mental retardation in children. There is no known liver detoxification pathway to excrete them. They are stored in body fat, and prevent weight-loss. The only way to get them out is high Iodine intake and sweating. The new DetoxBox combines dry heat sauna with beneficial Far Infrared light/heat. I now sell this very inexpensive yet sophisticated portable DetoxBox by special order. Cost is $299.

See article, photos, and specifications on the DetoxBox under News & Articles.


REFERENCES

1. Brownstein, D., Iodine: Why You Need It: Why You Can’t Live Without It, Medical Alternatives Press, West Bloomfield, Michigan, 2006.

2. Beck, L., The Good, The Bad & The Ugly, Seminar Manual, 2006.

3. Iodine Nutrition – More Is Better, New England Journal of Medicine, Vol 354: pages 2819-2821; June 29, 2006.

4. Pelletier C., Doucet E., Imbeault P., Tremblay A., Associations between weight loss-induced changes in plasma organochlorine concentrations, serum T3 concentration, and resting metabolic rate, Toxicol Sci., 67 (1): 46-51, May 2002.

5. Abraham,G.E., The Original Internist, 11:17-36, 2004.

6. Abraham, G.E., Flechas, J.D., Hakala, J.C., The Original Internist, 9:30-41, 2002.

7. Abraham, G.E., The Original Internist, 11:(2) 29-38, 2004.

8. Abraham, G.E. Townsend Letter, 245:100-101, 2003.

9. Abraham, G.E., Flechas, J.D., Hakala, J.C., The Original Internist, 9:5-20, 2002.


 


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